With Newtown flying the local flag in the fourth round of the Welsh Cup, most of the rest of the local action centres on league matches.
Guilsfield will be out to maintain their top three push in the JD Cymru North at home to Llandudno while Llanfair United will be searching for a lifeline victory at Llangefni.
MMP Mid Wales leaders Llanidloes will look to tighten their grip on the trophy at Kerry, while Welshpool Town host Aberaeron and Berriew travel to Four Crosses. Caersws and Carno are at home.
Abermule, Waterloo Rovers and Churchstoke hit the road in Division Two and there are home matches for Forden United and Dyffryn Banw.
There is also plenty of action in the JT Hughes Montgomeryshire League, but favourites Guilsfield Reserves travel to Trefonon for a cup match.
JD Welsh Cup, fourth round
Newtown v Rhyl
JD Cymru North
Guilsfield v Llandudno
Llangefni Town v Llanfair United
MMP Mid Wales League
Division One
Bow Street v Montgomery Town
Builth Wells v Llansantffraid
Caersws v Tywyn Bryncrug
Carno v Radnor Valley
Four Crosses v Berriew
Kerry v Llanidloes Town
Welshpool v Aberaeron
Division Two
Aber Uni v Abermule
Borth Utd v Waterloo Rovers
Dolgellau v Penparcau
Dyffryn Banw v Newbridge-on-Wye
Forden Utd v Rhayader
Knighton Town v Churchstoke
Presteigne v Machynlleth
JT Hughes Montgomeryshire League
Division One
Bishops Castle v Llanfair United Reserves
Llangedwyn v Llanrhaeadr Reserves
Maesyrhandir v Llanfyllin Town
Trewern v Meifod
Division Two
Churchstoke Reserves v Four Crosses Reserves
Llanfyllin Town Reserves v Kerry Reserves
Llanfechain v Welshpool Town Reserves
Newtown Wanderers v Caersws Reserves
Boys and Boden Montgomeryshire League Cup, second round
Waterloo Rovers Reserves v Llanymynech
Llansantffraid Village Cup, second round
Trefonen v Guilsfield Reserves