With a top six place already secured, Newtown will be looking to enjoy their final first phase match of the JD Welsh Premier season before the league splits in two.
Visitors Cefn Druids are resigned to life in the second tier, but will be hoping to catch a Newtown side off guard after they went down 4-0 to TNS last week.
Manager Chris Hughes said his Robins are at full strength, with Shrewsbury Town loan signing George Hughes expected to figure.
The Robins will also be hoping to finish the phase unbeaten at home following seven wins and three draws in the league this season.
Meanwhile, Guilsfield and Llanraeadr will be looking to get back to winning ways in the Huws Gray Alliance.
League defeats last weekend were followed by tough midweek Central Wales Cup matches which saw Llanrhaeadr edge Rhayader 4-2, but inconsistent Guilsfield slump to a shock home defeat on penalties against Radnor Valley.
On Saturday, Guilsfield travel to Gresford Athletic, while Llanrhaeadr host Holyhead Hotspur.
Our last two remaining teams in the fifth round of the FAW Trophy both hit the road as they bid to reach the last eight. Berriew head to Plas Madoc while Four Crosses travel to Bodedern Athletic.
MMP Mid Wales League leaders Llanidloes Town host local rivals Carno, while Caersws look to build some rhythm at Builth Wells after a disappointing month. Welshpool Town, with new signing Jack Harris, host Llansantffraid Village.
In Division Two, Montgomery Town and Waterloo Rovers face tricky away days.
The amateur league sees a mix of league and cup games, with Division One title chasers Forden United heading to Llanfyllin Town.
CWFA Senior Cup, Round Three draw (February)
Builth Wells v Hay St Marys; Welshpool v Four Crosses; Radnor Valley v Caersws; Berriew v Twywn/Bryncrug; Llanrhaeadr YM v Talgarth; Kerry v Carno; Llanfair United v Llanidloes; Abermule v Bow Street.
Saturday fixtures
JD Welsh Premier
Newtown v Cefn Druids
Saturday
Huws Gray Alliance
Gresford Athletic v Guilsfield
Llanrhaeadr v Holyhead Hotspur
FAW Trophy
Bodedern Athletic v Four Crosses
Plas Madoc v Berriew
MMP Mid Wales League
Division One
Aberaeron v Kerry
Builth Wells v Caersws
Llandrindod Wells v Churchstoke
Llanidloes v Carno
Tywyn Bryncrug v Llanfair United
Welshpool v Llansantffraid Village
Division Two
Abermule v Newbridge-on-Wye
Borth Utd v Montgomery
Dolgellau v Machynlleth
Presteigne v Hay St Mary's
Rhayader v Waterloo Rovers
JT Hughes Montgomeryshire League
Honda One
Llanfair United Reserves v Trewern
Llanfyllin Town v Forden United
Mitsubishi Two
Churchstoke Reserves v Llansantffraid Reserves
Llanwddyn v Abermule Reserves
Llanymynech v Welshpool Town Reserves
Newtown Wanderers v Llanfyllin Town Reserves
Waterloo Rovers Reserves v Llanfechain
Boys & Boden League Cup, round two
Four Crosses Reserves v Maesyrhandir
Boys & Boden League Cup, round three
Kerry Reserves v Bishops Castle
Meifod v Llanrhaeadr Reserves