Police have confirmed yesterday's operation in Shortbridge Street and Market Street was connected with a drugs warrant.
In a statement today they said: "Dyfed-Powys Police executed a warrant under the misuse of drugs act at Market Street, Newtown, at around 5pm on September 12.
"Two men were taken to hospital from the address, suspected of concealing drugs. A man and woman were arrested on suspicion of supplying class A drugs, at a separate location.
"They remain in police custody at this time. A police cordon remains in the area while searches continue at the property today."
Armed officers were involved in the raid which saw roads in the area closed.